Céline Denais

Céline Denais

Céline was born in Marseille and raised in Saint Quentin en Yvelines situated in the suburb of Paris.

She has always cultivated a tremendous interest in disciplines related to Medical Sciences. Her motivation relied on understanding the why of things. She naturally followed the path of biology and obtained a Bachelor in Biochemistry, a M1 in Cell Signalling and Integrative Neurosciences and a M2 in Cancerology from the University Paris-Saclay.

Her thirst for knowledge towards new emerging fields drove her across the Channel where she completed a PhD in Molecular Genetics at King’s College London under the supervision of Professor Richard Trembath. The work she performed was to investigate the molecular aetiology of a rare skeletal dysplasia Syndrome (DMC: Dyygve-Melchior-Clausen) particularly in defining the role and function of the dymeclin protein responsible for this disease.

She then moved to the United States where she carried out a postdoc in Dr Jan Lammerding’s laboratory at Cornell University for 5 years. Her interest in cancer pathways had fully bloomed since she studied how lamins influenced nuclear events during migration of metastatic cells under mechanical constraints. There, she gained a set of unique techniques utilizing cutting edge technologies and decided to apply her newly acquired interdisciplinary background back to Europe.

She became a member of Professor Sam Janes’ team at UCL in 2016. Her research agenda was to develop novel and innovative techniques for identifying key mechanical parameters that regulate lung cancer metastasis. To accomplish this goal, she used her expertise in the microfluidic technology to mimic complex biological systems but she also complemented her scope of techniques by getting access to valuable tools such as patient donors’ databank or “omic” sequencing.

She recently joined the MILE team to understand the cellular and molecular mechanisms triggered by mechanical stress on pancreatic tumor progression and its links with genomic instability.


Current members

Sanzhar Aitbay
PhD student

Team 17, CRCT 

MILE team, LAAS-CNRS

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Lucie Albert
PhD student

MILE team, LAAS-CNRS

MMBM team, IPGG

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Baptiste Alric
Post-doc

MILE team, LAAS-CNRS

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Céline Denais
Post-doc

MILE team, LAAS-CNRS

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Térence Desclaux
PhD student

IMFT

MILE team, LAAS-CNRS

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Mickaël Di Luoffo
Post-doc

Team 17, CRCT 

MILE team, LAAS-CNRS (invited)

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Julien Faccini
Research Engineer

MILE team, LAAS-CNRS

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Claire Lac
PhD student

Team 6, CRCT

MILE team, LAAS-CNRS

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Laure Le Blanc
PhD student

Pathog. vasc. infec., Inst. Pasteur

MILE team, LAAS-CNRS

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Stéphanie Mateo
PhD student

MILE team, LAAS-CNRS

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Morgan Delarue
CNRS researcher

MILE team, LAAS-CNRS

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Alumni

G. Lemercier
Post doc

10/2018-06/2019

Engineer @ Cardiorenal

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P. Lefebvre
Post doc

09/2019-08/2020

Assistant prof. @ Univ. Lorraine 

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Z. Ben Meriem
Post doc

01/2019-06/2022

Engineer @ SmartCatch

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I. Rizzuti
PhD student

09/2018-12/2019

Safety associate @ PPD

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X. Zhao
M2 student

03/2019-09/2019

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M. Moré
M2 student

02/2019-07/2019

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J. Bos
M1 student

03/2020-09/2020

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S. Goimard
M2 student

03/2021-07/2021

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N. El Fassi
M2 student

02/2022-07/2022

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E. Gaich
M2 student

02/2022-07/2022

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